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Crystallization and X-ray diffraction of LGN in complex with the actin-binding protein afadin

Asymmetric stem-cell divisions are fundamental for morphogenesis and tissue homeostasis. They rely on the coordination between cortical polarity and the orientation of the mitotic spindle, which is orchestrated by microtubule pulling motors recruited at the cortex by NuMA–LGN–Gαi complexes. LGN has...

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Publicat a:Acta Crystallogr F Struct Biol Commun
Autors principals: Carminati, Manuel, Cecatiello, Valentina, Mapelli, Marina
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741196/
https://ncbi.nlm.nih.gov/pubmed/26841766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16000807
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