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C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation. Here we show that C1q, but not C4, is expressed in the stroma and vascular endothelium of several human malignant tumours. Compared with wild-type...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4740357/ https://ncbi.nlm.nih.gov/pubmed/26831747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10346 |
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