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C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation. Here we show that C1q, but not C4, is expressed in the stroma and vascular endothelium of several human malignant tumours. Compared with wild-type...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4740357/ https://ncbi.nlm.nih.gov/pubmed/26831747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10346 |
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