Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis

Pericardial tuberculosis (TB) is associated with high therapy failure and high mortality rates. Antibiotics have to penetrate to site of infection at sufficient non-protein bound concentrations, and then enter bacteria to inhibit intracellular biochemical processes. The antibiotic concentrations ach...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Shenje, Justin, Ifeoma Adimora-Nweke, F., Ross, Ian L., Ntsekhe, Mpiko, Wiesner, Lubbe, Deffur, Armin, McIlleron, Helen M., Pasipanodya, Jotam, Gumbo, Tawanda, Mayosi, Bongani M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740291/
https://ncbi.nlm.nih.gov/pubmed/26870790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.09.025
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