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Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis

Pericardial tuberculosis (TB) is associated with high therapy failure and high mortality rates. Antibiotics have to penetrate to site of infection at sufficient non-protein bound concentrations, and then enter bacteria to inhibit intracellular biochemical processes. The antibiotic concentrations ach...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Shenje, Justin, Ifeoma Adimora-Nweke, F., Ross, Ian L., Ntsekhe, Mpiko, Wiesner, Lubbe, Deffur, Armin, McIlleron, Helen M., Pasipanodya, Jotam, Gumbo, Tawanda, Mayosi, Bongani M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740291/
https://ncbi.nlm.nih.gov/pubmed/26870790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.09.025
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