Ranking Fragment Ions Based on Outlier Detection for Improved Label-Free Quantification in Data-Independent Acquisition LC-MS/MS

Data-independent acquisition LC-MS/MS techniques complement supervised methods for peptide quantification. However, due to the wide precursor isolation windows, these techniques are prone to interference at the fragment ion level, which in turn is detrimental for accurate quantification. The “non-ou...

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Veröffentlicht in:J Proteome Res
Hauptverfasser: Bilbao, Aivett, Zhang, Ying, Varesio, Emmanuel, Luban, Jeremy, Strambio-De-Castillia, Caterina, Lisacek, Frédérique, Hopfgartner, Gérard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739871/
https://ncbi.nlm.nih.gov/pubmed/26412574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00394
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