Real-time analysis of the effects of toxic, therapeutic and sub-therapeutic concentrations of digitoxin on lung cancer cells

Digitoxin belongs to a naturally occurring class of cardiac glycosides (CG); digitoxin is clinically approved for heart failure and known for its anti-cancer effects against non-small lung cancer cells (NSCLC). However, concerns associated with its narrow therapeutic index and its concentration-depe...

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Bibliographic Details
Published in:Biosens Bioelectron
Main Authors: Eldawud, R., Stueckle, T.A., Manivannan, S., Elbaz, H., Chen, M., Rojanasakul, Y., Dinu, C.Z.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739845/
https://ncbi.nlm.nih.gov/pubmed/24727605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2014.03.030
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