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Alteration in Expression and Methylation of IGF2/H19 in Placenta and Umbilical Cord Blood Are Associated with Macrosomia Exposed to Intrauterine Hyperglycemia

OBJECTIVE: Macrosomia is one of the most common complications in gestational diabetes mellitus. Insulin-like growth factor 2 and H19 are two of the imprinted candidate genes that are involved in fetal growth and development. Change in methylation at differentially methylated region of the insulin-li...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Su, Rina, Wang, Chen, Feng, Hui, Lin, Li, Liu, Xinyue, Wei, Yumei, Yang, Huixia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739655/
https://ncbi.nlm.nih.gov/pubmed/26840070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148399
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