Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4(+) T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host

Ehrlichia chaffeensis is a tick-borne rickettsial pathogen and the causative agent of human monocytic ehrlichiosis. Transmitted by the Amblyomma americanum tick, E. chaffeensis also causes disease in several other vertebrate species including white-tailed deer and dogs. We have recently described th...

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Bibliographic Details
Published in:PLoS One
Main Authors: McGill, Jodi L., Nair, Arathy D. S., Cheng, Chuanmin, Rusk, Rachel A., Jaworski, Deborah C., Ganta, Roman R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739596/
https://ncbi.nlm.nih.gov/pubmed/26841025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148229
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