Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis

Targeting tumor angiogenesis is a promising alternative strategy for improvement of breast cancer therapy. Robo4 (roundabout homolog 4) signaling has been shown to protect endothelial integrity during sepsis shock and arthritis, and inhibit Vascular Endothelial Growth Factor (VEGF) signaling during...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Zhao, Helong, Ahirwar, Dinesh K., Oghumu, Steve, Wilkie, Tasha, Powell, Catherine A., Nasser, Mohd W., Satoskar, Abhay R., Li, Dean Y., Ganju, Ramesh K.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739522/
https://ncbi.nlm.nih.gov/pubmed/26778715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.10.007
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