NEUROTOXICOLOGY OF bis(n)-TACRINES ON Blattella germanica AND Drosophila melanogaster ACETYLCHOLINESTERASE

A series of bis(n)-tacrines were used as pharmacological probes of the acetylcholinesterase (AChE) catalytic and peripheral sites of Blattella germanica and Drosophila melanogaster, which express AChE-1 and AChE-2 isoforms, respectively. In general, the potency of bis(n)-tacrines was greater in D. m...

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Detalhes bibliográficos
Publicado no:Arch Insect Biochem Physiol
Main Authors: Mutunga, James M., Boina, DhanaRaj, Anderson, Troy D., Bloomquist, Jeffrey R., Carlier, Paul R., Wong, Dawn M., Lam, Polo C.-H., Totrov, Maxim. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739519/
https://ncbi.nlm.nih.gov/pubmed/23740645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/arch.21104
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