Aurora kinase targeting in lung cancer reduces KRAS-induced transformation

BACKGROUND: Activating mutations in KRAS are prevalent in lung cancer and have been causally linked to the oncogenic process. However, therapies targeted to oncogenic RAS have been ineffective to date and identification of KRAS targets that impinge on the oncogenic phenotype is warranted. Based on p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cancer
Egile Nagusiak: dos Santos, Edmilson Ozorio, Carneiro-Lobo, Tatiana Correa, Aoki, Mateus Nobrega, Levantini, Elena, Bassères, Daniela Sanchez
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739397/
https://ncbi.nlm.nih.gov/pubmed/26842935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0494-6
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