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Aurora kinase targeting in lung cancer reduces KRAS-induced transformation
BACKGROUND: Activating mutations in KRAS are prevalent in lung cancer and have been causally linked to the oncogenic process. However, therapies targeted to oncogenic RAS have been ineffective to date and identification of KRAS targets that impinge on the oncogenic phenotype is warranted. Based on p...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4739397/ https://ncbi.nlm.nih.gov/pubmed/26842935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0494-6 |
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