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Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcoma

BACKGROUND: Uterine carcinosarcoma (UCS) represents a true example of cancer associated with epithelial-mesenchymal transition (EMT), which exhibits cancer stem cell (CSC)-like traits. Both Sox and β-catenin signal transductions play key roles in the regulation of EMT/CSC properties, but little is k...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Inoue, Hisako, Takahashi, Hiroyuki, Hashimura, Miki, Eshima, Koji, Akiya, Masashi, Matsumoto, Toshihide, Saegusa, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739330/
https://ncbi.nlm.nih.gov/pubmed/26841870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2090-y
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