Requirement of the Akt/β-Catenin Pathway for Uterine Carcinosarcoma Genesis, Modulating E-Cadherin Expression Through the Transactivation of Slug

Uterine carcinosarcomas (UCSs) are considered to represent true examples of the epithelial-mesenchymal transition. Akt plays a key role in the induction of epithelial-mesenchymal transition, but little is known about its involvement in tumorigenesis. Here we examined the functional roles of the Akt/...

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Hlavní autoři: Saegusa, Makoto, Hashimura, Miki, Kuwata, Takeshi, Okayasu, Isao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2009
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684176/
https://ncbi.nlm.nih.gov/pubmed/19389926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081018
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