Localizing the lipid products of PI3Kγ in neutrophils

Class I phosphoinositide 3-kinases (PI3Ks) are important regulators of neutrophil migration in response to a range of chemoattractants. Their primary lipid products PtdIns(3,4,5)P(3) and PtdIns(3,4)P(2) preferentially accumulate near to the leading edge of migrating cells and are thought to act as a...

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Detalhes bibliográficos
Publicado no:Adv Biol Regul
Main Authors: Norton, Laura, Lindsay, Yvonne, Deladeriere, Arnaud, Chessa, Tamara, Guillou, Hervé, Suire, Sabine, Lucocq, John, Walker, Simon, Andrews, Simon, Segonds-Pichon, Anne, Rausch, Oliver, Finan, Peter, Sasaki, Takehiko, Du, Cheng-Jin, Bretschneider, Till, Ferguson, G. John, Hawkins, Phillip T., Stephens, Len
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739120/
https://ncbi.nlm.nih.gov/pubmed/26596865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2015.10.005
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