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Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1

In vitro and in vivo imaging of protein tyrosine kinase activity requires minimally invasive, molecularly precise optical probes to provide spatiotemporal mechanistic information of dimerization and complex formation with downstream effectors. We present here a construct with genetically encoded, si...

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Detalhes bibliográficos
Publicado no:Adv Biol Regul
Main Authors: Perdios, Louis, Bunney, Tom D., Warren, Sean C., Dunsby, Christopher, French, Paul M.W., Tate, Edward W., Katan, Matilda
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739061/
https://ncbi.nlm.nih.gov/pubmed/26482290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2015.09.002
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