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Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1
In vitro and in vivo imaging of protein tyrosine kinase activity requires minimally invasive, molecularly precise optical probes to provide spatiotemporal mechanistic information of dimerization and complex formation with downstream effectors. We present here a construct with genetically encoded, si...
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Publicado no: | Adv Biol Regul |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4739061/ https://ncbi.nlm.nih.gov/pubmed/26482290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2015.09.002 |
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