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The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase
Aldehyde oxidase (AO) is a complex molybdo-flavoprotein that belongs to the xanthine oxidase family. AO is active as a homodimer, and each 150-kDa monomer binds two distinct [2Fe2S] clusters, FAD, and the molybdenum cofactor. AO has an important role in the metabolism of drugs based on its broad sub...
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| 出版年: | Drug Metab Dispos |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Pharmacology and Experimental Therapeutics
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738704/ https://ncbi.nlm.nih.gov/pubmed/22279051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.043828 |
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