The First Mammalian Aldehyde Oxidase Crystal Structure: INSIGHTS INTO SUBSTRATE SPECIFICITY

Aldehyde oxidases (AOXs) are homodimeric proteins belonging to the xanthine oxidase family of molybdenum-containing enzymes. Each 150-kDa monomer contains a FAD redox cofactor, two spectroscopically distinct [2Fe-2S] clusters, and a molybdenum cofactor located within the protein active site. AOXs ar...

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Hlavní autoři: Coelho, Catarina, Mahro, Martin, Trincão, José, Carvalho, Alexandra T. P., Ramos, Maria João, Terao, Mineko, Garattini, Enrico, Leimkühler, Silke, Romão, Maria João
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504782/
https://ncbi.nlm.nih.gov/pubmed/23019336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390419
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