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Positional cloning of the hereditary renal carcinoma 3;8 chromosome translocation breakpoint.

The chromosome (p14.2;q24.1) translocation t(3;8) has been associated with hereditary renal cancer in one family. Based on cytogenetic analyses and loss-of-heterozygosity experiments, the 3p14 region has been independently implicated as harboring a tumor suppressor gene critical to kidney and lung c...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Boldog, F L, Gemmill, R M, Wilke, C M, Glover, T W, Nilsson, A S, Chandrasekharappa, S C, Brown, R S, Li, F P, Drabkin, H A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47386/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7690964/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8509
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