Catalytically active tissue transglutaminase colocalises with Aβ pathology in Alzheimer’s disease mouse models

Alzheimer’s disease (AD) is characterised by amyloid-beta (Aβ) protein deposition in the brain. Posttranslational modifications in Aβ play an important role in Aβ deposition. Tissue transglutaminase (tTG) is an enzyme involved in posttranslational cross-linking of proteins. tTG levels and activity a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Wilhelmus, Micha M. M., de Jager, Mieke, Smit, August B., van der Loo, Rolinka J., Drukarch, Benjamin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738336/
https://ncbi.nlm.nih.gov/pubmed/26837469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20569
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