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Catalytically active tissue transglutaminase colocalises with Aβ pathology in Alzheimer’s disease mouse models
Alzheimer’s disease (AD) is characterised by amyloid-beta (Aβ) protein deposition in the brain. Posttranslational modifications in Aβ play an important role in Aβ deposition. Tissue transglutaminase (tTG) is an enzyme involved in posttranslational cross-linking of proteins. tTG levels and activity a...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738336/ https://ncbi.nlm.nih.gov/pubmed/26837469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20569 |
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