BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit

The over-expressed colonic brain-derived neurotrophic factor (BDNF) has been reported to be associated with abdominal pain in patients with irritable bowel syndrome (IBS). However, the neuropathological mechanism is unclear. We here investigated the involvement of enteroglial cells (EGCs) and enteri...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Peng, Du, Chao, Chen, Fei-Xue, Li, Chang-Qing, Yu, Yan-Bo, Han, Ting, Akhtar, Suhail, Zuo, Xiu-Li, Tan, Xiao-Di, Li, Yan-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738267/
https://ncbi.nlm.nih.gov/pubmed/26837784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20320
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