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MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma

The molecular mechanisms underlying the aggressive behavior of MYCN driven neuroblastoma (NBL) is under intense investigation; however, little is known about the impact of this family of transcription factors on the splicing program. Here we used high-throughput RNA sequencing to systematically stud...

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Bibliographic Details
Published in:Cancer Lett
Main Authors: Zhang, Shile, Wei, Jun S., Li, Samuel Q., Badgett, Tom C., Song, Young K., Agarwal, Saurabh, Coarfa, Cristian, Tolman, Catherine, Hurd, Laura, Liao, Hongling, He, Jianbin, Wen, Xinyu, Liu, Zhihui, Thiele, Carol J., Westermann, Frank, Asgharzadeh, Shahab, Seeger, Robert C., Maris, John M., Auvil, Jamie M Guidry, Smith, Malcolm A, Kolaczyk, Eric D, Shohet, Jason, Khan, Javed
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738031/
https://ncbi.nlm.nih.gov/pubmed/26683771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.11.045
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