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MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma

The molecular mechanisms underlying the aggressive behavior of MYCN driven neuroblastoma (NBL) is under intense investigation; however, little is known about the impact of this family of transcription factors on the splicing program. Here we used high-throughput RNA sequencing to systematically stud...

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Bibliografiska uppgifter
I publikationen:Cancer Lett
Huvudupphovsmän: Zhang, Shile, Wei, Jun S., Li, Samuel Q., Badgett, Tom C., Song, Young K., Agarwal, Saurabh, Coarfa, Cristian, Tolman, Catherine, Hurd, Laura, Liao, Hongling, He, Jianbin, Wen, Xinyu, Liu, Zhihui, Thiele, Carol J., Westermann, Frank, Asgharzadeh, Shahab, Seeger, Robert C., Maris, John M., Auvil, Jamie M Guidry, Smith, Malcolm A, Kolaczyk, Eric D, Shohet, Jason, Khan, Javed
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738031/
https://ncbi.nlm.nih.gov/pubmed/26683771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.11.045
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