Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia.

To develop an effective strategy to prevent neointima formation after angioplasty injury, we have identified cell-cycle regulatory proteins as targets for inhibition by using antisense oligonucleotides (ODNs). We utilized an intraluminal molecular delivery method that employs the protein coat of a S...

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Detalles Bibliográficos
Main Authors: Morishita, R, Gibbons, G H, Ellison, K E, Nakajima, M, Zhang, L, Kaneda, Y, Ogihara, T, Dzau, V J
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC47379/
https://ncbi.nlm.nih.gov/pubmed/8104336
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