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Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia.

To develop an effective strategy to prevent neointima formation after angioplasty injury, we have identified cell-cycle regulatory proteins as targets for inhibition by using antisense oligonucleotides (ODNs). We utilized an intraluminal molecular delivery method that employs the protein coat of a S...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Morishita, R, Gibbons, G H, Ellison, K E, Nakajima, M, Zhang, L, Kaneda, Y, Ogihara, T, Dzau, V J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47379/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8104336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8474
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