Rescue of Cyclic AMP Mediated Long Term Potentiation Impairment in the Hippocampus of Mecp2 Knockout (Mecp2(-/y)) Mice by Rolipram

Rett syndrome (RTT) patients experience learning difficulties and memory loss. Analogous deficits of hippocampal plasticity are reported in mouse models of RTT. To elucidate the underlying pathophysiology, we studied long term potentiation (LTP) at the CA3 to CA1 synapses in the hippocampus in acute...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Neurosci
Asıl Yazarlar: Balakrishnan, Saju, Niebert, Marcus, Richter, Diethelm W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2016
Konular:
Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737891/
https://ncbi.nlm.nih.gov/pubmed/26869885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00015
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