Antibodies Against Glycolipids Enhance Antifungal Activity of Macrophages and Reduce Fungal Burden After Infection with Paracoccidioides brasiliensis

Paracoccidioidomycosis is a fungal disease endemic in Latin America. Polyclonal antibodies to acidic glycosphingolipids (GSLs) from Paracoccidioides brasiliensis opsonized yeast forms in vitro increasing phagocytosis and reduced the fungal burden of infected animals. Antibodies to GSL were active in...

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Udgivet i:Front Microbiol
Main Authors: Bueno, Renata A., Thomaz, Luciana, Muñoz, Julian E., da Silva, Cássia J., Nosanchuk, Joshua D., Pinto, Márcia R., Travassos, Luiz R., Taborda, Carlos P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737878/
https://ncbi.nlm.nih.gov/pubmed/26870028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00074
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