Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing

A chromosome is composed of structurally and functionally distinct domains. However, the molecular mechanisms underlying the formation of chromatin structure and the function of subtelomeres, the telomere-adjacent regions, remain obscure. Here we report the roles of the conserved centromeric protein...

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Udgivet i:Nat Commun
Main Authors: Tashiro, Sanki, Handa, Tetsuya, Matsuda, Atsushi, Ban, Takuto, Takigawa, Toru, Miyasato, Kazumi, Ishii, Kojiro, Kugou, Kazuto, Ohta, Kunihiro, Hiraoka, Yasushi, Masukata, Hisao, Kanoh, Junko
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737732/
https://ncbi.nlm.nih.gov/pubmed/26804021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10393
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