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Tributyltin engages multiple nuclear receptor pathways and suppresses osteogenesis in bone marrow multipotent stromal cells

Organotins are members of the environmental obesogen class of contaminants because they activate peroxisome proliferator-activated receptor γ (PPARγ), the essential regulator of adipogenesis. Exposure to thiazolidinediones, PPARγ ligands used to treat type 2 diabetes, is associated with increased fr...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Res Toxicol
Egile Nagusiak: Baker, Amelia H., Watt, James, Huang, Cassie K., Gerstenfeld, Louis C., Schlezinger, Jennifer J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737589/
https://ncbi.nlm.nih.gov/pubmed/25932594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500433r
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