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Tributyltin engages multiple nuclear receptor pathways and suppresses osteogenesis in bone marrow multipotent stromal cells
Organotins are members of the environmental obesogen class of contaminants because they activate peroxisome proliferator-activated receptor γ (PPARγ), the essential regulator of adipogenesis. Exposure to thiazolidinediones, PPARγ ligands used to treat type 2 diabetes, is associated with increased fr...
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| Publicado no: | Chem Res Toxicol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4737589/ https://ncbi.nlm.nih.gov/pubmed/25932594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500433r |
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