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Differential role of the Ca(2+) sensor synaptotagmin VII in macrophages and dendritic cells

Synaptotagmin VII (Syt VII) is a Ca(2+) sensing molecule that regulates lysosomal exocytosis in several cell types. In macrophages (MØ), Syt VII is required for efficient uptake of large particle loads, by promoting the delivery of lysosomal membrane to phagocytic cups. Here we compare the phagocyti...

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Publicat a:Immunobiology
Autors principals: Becker, Steven M., Delamarre, Lélia, Mellman, Ira, Andrews, Norma W.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737586/
https://ncbi.nlm.nih.gov/pubmed/19157638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2008.11.006
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