Inhibition of CaMKK2 Reverses Age-Associated Decline in Bone Mass

Decline in bone formation is a major contributing factor to the loss of bone mass associated with aging. We previously showed that the genetic ablation of the tissue-restricted and multifunctional Ca(2+)/calmodulin (CaM)-dependent protein kinase kinase 2 (CaMKK2) stimulates trabecular bone mass accr...

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Udgivet i:Bone
Main Authors: Pritchard, Zachary J., Cary, Rachel L., Yang, Chang, Novack, Deborah V., Voor, Michael J., Sankar, Uma
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737584/
https://ncbi.nlm.nih.gov/pubmed/25724145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.01.021
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