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Androgen Receptor-CaMKK2 Axis in Prostate Cancer and Bone Microenvironment
The skeletal system is of paramount importance in advanced stage prostate cancer (PCa) as it is the preferred site of metastasis. Complex mechanisms are employed sequentially by PCa cells to home to and colonize the bone. Bone-resident PCa cells then recruit osteoblasts (OBs), osteoclasts (OCs), and...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Frontiers Media S.A.
2018-06-01
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Colecção: | Frontiers in Endocrinology |
Assuntos: | |
Acesso em linha: | https://www.frontiersin.org/article/10.3389/fendo.2018.00335/full |
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