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High-Throughput Assay of 9 Lysosomal Enzymes for Newborn Screening

BACKGROUND: There is interest in newborn screening of lysosomal storage diseases (LSDs) because of the availability of treatments. Pilot studies have used tandem mass spectrometry with flow injection of samples to achieve multiplex detection of enzyme products. We report a multiplexing method of 9 e...

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Bibliografische gegevens
Gepubliceerd in:Clin Chem
Hoofdauteurs: Spacil, Zdenek, Tatipaka, Haribabu, Barcenas, Mariana, Scott, C. Ronald, Turecek, Frantisek, Gelb, Michael H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737435/
https://ncbi.nlm.nih.gov/pubmed/23315484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2012.189936
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