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Review article: inhibition of methanogenic archaea by statins as a targeted management strategy for constipation and related disorders

BACKGROUND: Observational studies show a strong association between delayed intestinal transit and the production of methane. Experimental data suggest a direct inhibitory activity of methane on the colonic and ileal smooth muscle and a possible role for methane as a gasotransmitter. Archaea are the...

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發表在:Aliment Pharmacol Ther
Main Authors: Gottlieb, K., Wacher, V., Sliman, J., Pimentel, M.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737270/
https://ncbi.nlm.nih.gov/pubmed/26559904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.13469
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