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Review article: inhibition of methanogenic archaea by statins as a targeted management strategy for constipation and related disorders
BACKGROUND: Observational studies show a strong association between delayed intestinal transit and the production of methane. Experimental data suggest a direct inhibitory activity of methane on the colonic and ileal smooth muscle and a possible role for methane as a gasotransmitter. Archaea are the...
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| Publicado no: | Aliment Pharmacol Ther |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4737270/ https://ncbi.nlm.nih.gov/pubmed/26559904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.13469 |
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