Polygenic risk of Parkinson disease is correlated with disease age at onset

OBJECTIVE: We have investigated the polygenic architecture of Parkinson disease (PD) and have also explored the potential relationship between an individual's polygenic risk score and their disease age at onset. METHODS: This study used genotypic data from 4,294 cases and 10,340 controls obtain...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Escott‐Price, Valentina, Nalls, Mike A., Morris, Huw R., Lubbe, Steven, Brice, Alexis, Gasser, Thomas, Heutink, Peter, Wood, Nicholas W., Hardy, John, Singleton, Andrew B., Williams, Nigel M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737223/
https://ncbi.nlm.nih.gov/pubmed/25773351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24335
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