CstF-64 and 3′-UTR cis-element determine Star-PAP specificity for target mRNA selection by excluding PAPα

Almost all eukaryotic mRNAs have a poly (A) tail at the 3′-end. Canonical PAPs (PAPα/γ) polyadenylate nuclear pre-mRNAs. The recent identification of the non-canonical Star-PAP revealed specificity of nuclear PAPs for pre-mRNAs, yet the mechanism how Star-PAP selects mRNA targets is still elusive. M...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Kandala, Divya T., Mohan, Nimmy, A, Vivekanand, AP, Sudheesh, G, Reshmi, Laishram, Rakesh S.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737136/
https://ncbi.nlm.nih.gov/pubmed/26496945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1074
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