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ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints

OBJECTIVE: The parasitic worm–derived immunomodulator ES‐62 protects against disease in the mouse collagen‐induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin‐17 (IL‐17) responses. The Th17‐associated cytokine IL‐22 also appears to have a pathogenic role...

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Dettagli Bibliografici
Pubblicato in:Arthritis Rheumatol
Autori principali: Pineda, Miguel A., Rodgers, David T., Al‐Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737104/
https://ncbi.nlm.nih.gov/pubmed/24497523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38392
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