ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints

OBJECTIVE: The parasitic worm–derived immunomodulator ES‐62 protects against disease in the mouse collagen‐induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin‐17 (IL‐17) responses. The Th17‐associated cytokine IL‐22 also appears to have a pathogenic role...

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Enregistré dans:
Détails bibliographiques
Publié dans:Arthritis Rheumatol
Auteurs principaux: Pineda, Miguel A., Rodgers, David T., Al‐Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2014
Sujets:
Experimental Arthritis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737104/
https://ncbi.nlm.nih.gov/pubmed/24497523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38392
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