Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice

The receptor activator of NF-κB ligand (RANKL) and its receptor RANK are overexpressed in focal segmental glomerular sclerosis (FSGS), IgA nephropathy (IgAN), and membranous nephropathy (MN). However, the expression and the potential roles of RANKL and RANK in diabetic nephropathy (DN) remain unclea...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Chen, Xiao-Wen, Du, Xiao-Yan, Wang, Yu-Xian, Wang, Jian-Cheng, Liu, Wen-Ting, Chen, Wen-Jing, Li, Hong-Yu, Peng, Fen-Fen, Xu, Zhao-Zhong, Niu, Hong-Xin, Long, Hai-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736580/
https://ncbi.nlm.nih.gov/pubmed/26880862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1405924
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