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Luciferase mRNA Transfection of Antigen Presenting Cells Permits Sensitive Nonradioactive Measurement of Cellular and Humoral Cytotoxicity

Immunotherapy is rapidly evolving as an effective treatment option for many cancers. With the emerging fields of cancer vaccines and adoptive cell transfer therapies, there is an increasing demand for high-throughput in vitro cytotoxicity assays that efficiently analyze immune effector functions. Th...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Omokoko, Tana A., Luxemburger, Uli, Bardissi, Shaheer, Simon, Petra, Utsch, Magdalena, Breitkreuz, Andrea, Türeci, Özlem, Sahin, Ugur
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736447/
https://ncbi.nlm.nih.gov/pubmed/27057556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9540975
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