Case report: Severe central nervous system manifestations associated with aberrant efavirenz metabolism in children: the role of CYP2B6 genetic variation

BACKGROUND: Efavirenz, widely used as part of antiretroviral drug regimens in the treatment of paediatric human immunodeficiency virus infection, has central nervous system side effects. We describe four children presenting with serious, persistent central nervous system adverse events who were foun...

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Detaylı Bibliyografya
Yayımlandı:BMC Infect Dis
Asıl Yazarlar: Pinillos, Francoise, Dandara, Collet, Swart, Marelize, Strehlau, Renate, Kuhn, Louise, Patel, Faeezah, Coovadia, Ashraf, Abrams, Elaine
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Case Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735961/
https://ncbi.nlm.nih.gov/pubmed/26831894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-1381-x
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