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Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients.

Chronic respiratory infections with mucoid Pseudomonas aeruginosa are the leading cause of high mortality and morbidity in cystic fibrosis (CF). The initially colonizing strains are nonmucoid, but in the CF lung they invariably convert into the mucoid, exopolysaccharide alginate-overproducing form c...

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Bibliographic Details
Main Authors: Martin, D W, Schurr, M J, Mudd, M H, Govan, J R, Holloway, B W, Deretic, V
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47359/
https://ncbi.nlm.nih.gov/pubmed/8378309
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