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Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients.

Chronic respiratory infections with mucoid Pseudomonas aeruginosa are the leading cause of high mortality and morbidity in cystic fibrosis (CF). The initially colonizing strains are nonmucoid, but in the CF lung they invariably convert into the mucoid, exopolysaccharide alginate-overproducing form c...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Martin, D W, Schurr, M J, Mudd, M H, Govan, J R, Holloway, B W, Deretic, V
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47359/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8378309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8377
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