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Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients.

Chronic respiratory infections with mucoid Pseudomonas aeruginosa are the leading cause of high mortality and morbidity in cystic fibrosis (CF). The initially colonizing strains are nonmucoid, but in the CF lung they invariably convert into the mucoid, exopolysaccharide alginate-overproducing form c...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Martin, D W, Schurr, M J, Mudd, M H, Govan, J R, Holloway, B W, Deretic, V
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1993
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47359/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8378309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8377
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