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Bacterial Muramyl Dipeptide (MDP) Restricts Human Cytomegalovirus Replication via an IFN-β-Dependent Pathway

We recently reported that induction of NOD2 by human Cytomegalovirus (HCMV) resulted in virus inhibition and upregulation of antiviral and inflammatory cytokines. Here we investigated the effects of muramyl dipeptide (MDP), a bacterial cell wall component that activates NOD2, on HCMV replication and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kapoor, Arun, Fan, Yi-Hsin, Arav-Boger, Ravit
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735818/
https://ncbi.nlm.nih.gov/pubmed/26830977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20295
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