KRAS mutation in lung metastases from colorectal cancer: prognostic implications

KRAS mutant colorectal cancer (CRC) patients develop lung and brain metastases more frequently than KRAS wild‐type (WT) counterpart. We retrospectively investigated the prognostic role of KRAS,BRAF, and PIK3CA (exon 20) mutations and loss of phosphatase and tensin homolog (PTEN) in surgically resect...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Ghidini, Michele, Personeni, Nicola, Bozzarelli, Silvia, Baretti, Marina, Basso, Gianluca, Bianchi, Paolo, Tronconi, Maria Chiara, Pressiani, Tiziana, Grizzi, Fabio, Giordano, Laura, Malesci, Alberto, Alloisio, Marco, Laghi, Luigi, Santoro, Armando, Rimassa, Lorenza
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Clinical Cancer Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735767/
https://ncbi.nlm.nih.gov/pubmed/26715198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.592
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