KRAS mutation in lung metastases from colorectal cancer: prognostic implications

KRAS mutant colorectal cancer (CRC) patients develop lung and brain metastases more frequently than KRAS wild‐type (WT) counterpart. We retrospectively investigated the prognostic role of KRAS,BRAF, and PIK3CA (exon 20) mutations and loss of phosphatase and tensin homolog (PTEN) in surgically resect...

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Bibliographic Details
Published in:Cancer Med
Main Authors: Ghidini, Michele, Personeni, Nicola, Bozzarelli, Silvia, Baretti, Marina, Basso, Gianluca, Bianchi, Paolo, Tronconi, Maria Chiara, Pressiani, Tiziana, Grizzi, Fabio, Giordano, Laura, Malesci, Alberto, Alloisio, Marco, Laghi, Luigi, Santoro, Armando, Rimassa, Lorenza
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
Subjects:
Clinical Cancer Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735767/
https://ncbi.nlm.nih.gov/pubmed/26715198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.592
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