Φορτώνει......
Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2
In chronic kidney disease (CKD), proteinuria results in severe tubulointerstitial lesions, which ultimately lead to end-stage renal disease. Here we identify 4-phenylbutyric acid (PBA), a chemical chaperone already used in humans, as a novel therapeutic strategy capable to counteract the toxic effec...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Commun |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2016
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4735759/ https://ncbi.nlm.nih.gov/pubmed/26787103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10330 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|