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The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts

In response to intracellular signals in Gram-negative bacteria, translational riboswitches—commonly embedded in messenger RNAs (mRNAs)—regulate gene expression through inhibition of translation initiation. It is generally thought that this regulation originates from occlusion of the Shine-Dalgarno (...

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Udgivet i:Nat Commun
Main Authors: Rinaldi, Arlie J., Lund, Paul E., Blanco, Mario R., Walter, Nils G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735710/
https://ncbi.nlm.nih.gov/pubmed/26781350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9976
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